Fine Organic Chemistry
Fine organic chemistry for custom synthesis :
- base and/or sugar modified nucleoside analogues
- mono-, di- and triphosphate nucleoside analogues
- phosphoramidites
- di-nucleotides
- mono & oligo/polysaccharides
- iminosugars
- sugar phosphates
- unnatural sugars
- saccharidic antigens, synthetic glycoconjugates
- heterobase analogues
- synthesis of sophisticated heterocyclic compounds (purine, pyrimidine, imidazole, thiophene, thiazole, pyrazole, quinoline…, including phosphorus and fluorine chemistry)
- mg to 20g synthesis of NCEs, building blocks, scaffolds, intermediates, reference products, competitor compounds, drug metabolites, impurities….
- collaboration with preferred external partners for 20g to Kg lab scale-up optimization and synthesis
Fine organic chemistry and optimization processes in other fields:
- nucleoside / nucleotide analogues (base and/or sugar modified analogues, phosphoramidites) as diagnostic or research tools
- fluorescent dyes for diagnostic applications
- optimization of small molecules as diagnostic kit reagents